Diethylstilbestrol (DES) exposed women and cervical screening

Women exposed in utero to Diethylstilbestrol (DES) should have an initial colposcopic examination. In the absence of an abnormality at that first examination, only routine cervical screening is required. Women whose initial examination showed an abnormality or stigmata of DES exposure may require annual colposcopic examination of the vagina and cervix, in specialist centres, possibly for life. However, this should be considered on an individual basis by the woman concerned and her gynaecologist.

Royal College of Obstetricians and Gynaecologists:
Statement on fetal and maternal risks of diethylstilbestrol exposure in pregnancy (PDF 100Kb).